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Compound comparisons

Receptor targets and molecular classes from published preclinical literature. Reference only — not health guidance.

Retatrutide vs Tirzepatide vs Semaglutide

These differ by how many receptors they target: semaglutide targets one (GLP-1), tirzepatide two (GIP + GLP-1) and retatrutide three (GIP + GLP-1 + glucagon).

CompoundClassTarget
SemaglutideAcylated GLP-1 analogGLP-1 receptor
TirzepatideSynthetic dual-agonist peptideGIP and GLP-1 receptors
RetatrutideSynthetic peptide tri-agonistGIP, GLP-1 and glucagon receptors

BPC-157 vs TB-500

BPC-157 is studied around nitric-oxide and VEGF signaling; TB-500 is a thymosin β4 fragment studied for actin binding and cell migration.

CompoundClassTarget
BPC-157Synthetic 15-amino-acid peptideNitric oxide and VEGF pathways
TB-500Thymosin β4 synthetic fragmentG-actin binding

CJC-1295 vs Ipamorelin

CJC-1295 is a GHRH analog acting on the GHRH receptor; ipamorelin is a secretagogue acting on the ghrelin receptor (GHS-R1a).

CompoundClassTarget
CJC-1295Modified GHRH analogGHRH receptor
IpamorelinSelective pentapeptide secretagogueGhrelin receptor (GHS-R1a)

Selank vs Semax

Both are synthetic neuropeptides: selank is a tuftsin analog studied in GABAergic models; semax is an ACTH(4-10) analog studied for BDNF expression.

CompoundClassTarget
SelankSynthetic tuftsin analog heptapeptideGABAergic and BDNF pathways
SemaxSynthetic ACTH(4-10) analogBDNF/TrkB and melanocortin pathways